The antimetabolite drug, 5fluorouracil 5fu, is used in the treatment of various cancers, including basal cell carcinomas bccs. In the who iarc classification of head and neck pathology, this clinical entity had been known. Clinically, the kot is manifested by an asymptomatic growth. Okc treatment is to meet the patients expectations regarding minimizing the adverse functional and esthetic side effects while at the same time to fully eliminate the pathology. Clinical symptoms are rarely observed, as it grows painless and silently through medullary bone. Orthokeratinized odontogenic cyst ooc is a relatively rare lesion of the jaws, mainly located in the posterior segment of the mandible 1,3. The case for decompression and marsupialization joms 2005. Tamoxifen citrate ici46474 is an antiestrogenic agent 1 used in cases of disseminated breast carcinomas and as adjuvant postoperative therapy. The authors report a case of penetration of an odontogenic keratocyst into the skull base. Multiple okcs are usually seen in association with nevoid basal cell carcinoma syndrome nbccs but approximately 5% of patients with okc have multiple cysts without concomitant syndromic presentation. An odontogenic keratocyst can develop at virtually any site in the jaws and is of concern because of its aggressive clinical behavior. Previously known as odontogenic keratocysts okcs, kots were subsequently reclassified as a tumor by the world health.
A case report on surgical management of odontogenic. As narrated by her father, the swelling was noted 6 weeks previously, while its size increased gradually, but progressively. Decompression or marsupialization seem to be more conservative options in the treatment of okc. Massive keratocystic odontogenic tumor of mandible. He had no signs or symptoms but a little pain when he went for his routine dental check. After removing the coronal restorations, the guttapercha was removed using a nickel titanium rotary instruments profile ori. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Otogenic definition of otogenic by medical dictionary. This free online tool allows to combine multiple pdf or image files into a single pdf document. Surgical treatment algorithm for odontogenic keratocyst. Keratocyst odontogenic tumor kcot is a benign neoplasm defined by the world health organization as a benign unicystic or multicystic, intraosseous tumor of odontogenic origin, with a characteristic lining of parakeratinized stratified squamous epithelium and a potential for aggressive, infiltrative behavior, and high recurrence rate.
The keratocyst odontogenic tumor has characteristics, with slow development, does not cause metastases and provides great bone destruction. The odontogenic keratocyst philipsen in 1956, while still a senior dental student working with jens j pindborg in copenhagen, named and described the odontogenic keratocyst. Dentsply maillefer, ballaigues, switzerland in the coronal and middle thirds of the roots. Apr, 2016 odontogenic keratocyst or keratocystic odontogengic tumor.
Discussion okc common location is in the mandibular angle and ramus. In radiographic evaluations for diagnosis, follow ups and before and after treatment, panoramic, 3d ct and mr images were. Odontogenic keratocysts make up around 19% of jaw cysts. Odontogenic keratocyst okc is an enigmatic developmental cyst, which mikulicz in 1876 first described it as a part of a familial condition affecting the jaws. J oral maxillofac surg eradication of the pathologic lesion, 10. Treatment methods at the second affiliated hospital of jiamusi university. There is significant controversy about what is the optimum surgical treatment for the odontogenic keratocyst. The earliest description of the syndrome has been attributed to otto sachs in 1903, who comprehe. The odontogenic keratocyst okc is a recurrent cyst that has been recently reclassified from an odontogenic tumor to an odontogenic cyst. Peripheral odontogenic keratocyst research nebraska.
Keratocystic odontogenic tumour, odontogenic keratocyst, p53 address for correspondence. Previously classified under developmental odontogenic cyst. Toxic reactions to tamoxifen, such as decreased visual acuity, bilateral macular edema, and yellowwhite dots in the paramacular and foveal areas, are relatively rare reported incidence between 0. Investigations continue into the lesions pathologic classification, diagnosis and. Odontogenic medical definition merriamwebster medical. We present here a case where surgical treatment and followup of a okc was achieved by a combination of minimalinvasive approaches. Aug 26, 20 the odontogenic keratocyst philipsen in 1956, 9 while still a senior dental student working with jens j pindborg in copenhagen, named and described the odontogenic keratocyst.
A 11yearold female patient reported to the outpatient department of modern dental college and research center, indore, in may 2010, with a complaint of swelling on the right side of the chin that caused considerable asymmetry of the face figure 1. Combined treatment of odontogenic keratocyst and mandibular defect with marsupialization, enucleation, iliac crest bone graft, and dental implants. Reports of bone erosion, 1 orbital invasion, 2 skull base extension, 3 and temporal fossa violation 4 show the aggressive nature of this lesion. Treatment and 3d image followup of a recurrent keratocyst. The treatment of odontogenic keratocysts by excision of the overlying, attached mucosa, enucleation, and treatment of the bony defect with carnoy solution. A case report on surgical management of odontogenic keratocyst. Systemic antibiotics in the treatment of periodontal disease. Appearance in an odontogenic keratocyst of the mandible. Dr nakisa torabinia, department of oral and maxillofacial pathology and torabinejad dental research center, school of dentistry, isfahan university of medical sciences, isfahan, iran. The okc is well known for its tendency to recur, potential aggressive behavior and defined histopathological feature. The odontogenic keratocyst can be defined as a cystic benign tumor, being localized at the level of the mandible or the maxilla. Eight consecutive patients submitted to fnac and diagnosed with okc were included in this study. The designation keratocyst was used to describe any jaw cyst in which keratin was formed to a large extent.
Fine needle aspiration cytology as an additional tool in the. Combine multiple pdf files into one single pdf document. Our pdf merger allows you to quickly combine multiple pdf files into one single pdf document, in just a few clicks. Pdf surgical treatment of keratocystic odontogenic. Treatment of an odontogenic keratocyst although there are promising new techniques to treat an odontogenic keratocyst, the most common method of treatment is simply going into the jawbone and removing the odontogenic keratocyst. The okc was designated by the world health organization who in 2005 as a keratocystic odontogenic tumor kcot and is defined as a benign uni or multicystic, intraosseous tumor of odontogenic origin, with a characteristic lining of parakeratinized stratified squamous epithelium and. Keratocystic odontogenic tumor kcotokcclinical guidelines. Pdf merge combine pdf files free tool to merge pdf online.
Five years followup of a keratocyst odontogenic tumor. An odontogenic keratocyst is a rare and benign but locally aggressive developmental cyst. Merge pdf online combine pdf files for free foxit software. Research article microbiology and antibiotic sensitivity of odontogenic space infection santosh an1, viresh an2, sharmada bk3 abstract background. Start studying nonodontogenic cyst in the oral cavity. Research article microbiology and antibiotic sensitivity. The aim of this study was to evaluate different surgical treatment methods for keratocystic odontogenic tumors kcots and the outcome of those treatments over a 9year period. Marsupialization was first described by partsch in 1882 for the treatment of cystic lesions.
Fine needle aspiration cytology as an additional tool in. Nyimi bushabu fidele 1, feng duan 1, em kalala kazadi 2, jian guan 1, mantshumba milolo augustin 3, yuwen zhou 4. The aim of this study was to discuss the aspects regarding the diagnosis, prognosis and treatment of odontogenic keratocyst tumor, through the report of two cases. Nonsurgical chemotherapeutic treatment strategies for the management of periodontal diseases. Odontogenic keratocyst associated with an ectopic tooth in. It is one of the most aggressive odontogenic cysts of the oral cavity.
In radiographic evaluations for diagnosis, follow ups and before and after treatment, panoramic, 3d ct and. Dental infections, including gingivitis, odontogenic infections periodontitis, dental caries and, result in frequentoral. The aim of the present study was to investigate its treatment and address. A 32yearold female patient showed a welldelimited radiolucent lesion connected with the root of the left third molar with close anatomical relationship with the mandibular canal. The aim of our study is to report the outcome of conservative treatment protocol for okc. The odontogenic keratocyst and its occurance in basel cell carcinoma. Select or drag your files, then click the merge button to download your document into one pdf file. In this paper, we shall present one case report of a keratocyst, which derived from an impacted canine. Peripheral odontogenic keratocyst is clinically aggressive and has the potential to recur as the classical odontogenic keratocyst 15.
Okc is known for its rapid growth and its tendency to invade the adjacent tissues including bone. Odontogenic keratocyst okc has been the subject of great interest since philipsen introduced the term in 1956. Many studies have been done about the treatment of kcot, but the recurrence rate still remains high despite the combination of surgical techniques used, associated with or without the use chemical solutions such as carnoys solution or cryosurgery. The odontogenic keratocyst is a distinctive developmental odontogenic cyst typically occurring in the jaws, with a predilection for the posterior body and ascending ramus of the mandible. The objective of the present study is to report a clinical case of a surgical treatment of a parakeratinized odontogenic keratocyst by enucleation in a fourteenyear old girl. Because acute telogen effluvium is a reactive process, which resolves spontaneously, treatment usually is limited to reassurance. Keratinocystic odontogenic tumor odontogenic keratocyst keratinocystic odontogenic tumor three important things associated with this diagnosis. The odontogenic keratocyst is an important part in the clinical features of basal cell nevus syndrome or gorlin and goltz syndrome. Odontogenic keratocyst symptoms, treatment, pictures.
Summary of available clinical data of all reported cases of odontogenic keratocyst associated with an ectopic tooth reference age yr gender concerned composition symptom treatment variant feature outcome hunter et al. Combine multiple pdf files into one pdf, try foxit pdf merge tool online free and easy to use. Jan 21, 2020 in the treatment of benign nodules and nontoxic multinodular goiter, tsh is generally suppressed to a higher target e. Fnac was performed using 24gauge needles attached to a 10. Treatment and cure for odontogenic keratocysts download here free healthcaremagic app to ask a doctor all the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. Case report multiple recurrent odontogenic keratocysts with. Learn about drug interactions between amiodarone oral and cyclosporine oral and use the rxlist drug interaction checker to check drug combinations. First described by philipsen in 1956, the odontogenic keratocyst is characterized by a large squamous keratinization of its border, an aggressive growth and a high recurrent rate.
Soda pdf merge tool allows you to combine pdf files in seconds. Lapointe table 1 description of keratocystic odontogenic tumours and treatment in a series of 21 patients patients date of 2birth tumour location size. Okc is now referred to by the world health organization who as a keratocystic odontogenic tumour kcot, and who defined it as a benign uni or multicystic, intraosseous tumour of odontogenic origin, with a characteristic lining of parakeratinized stratified. The odontogenic keratocyst okc was first described and named by phillipsen in 1956. Odontogenic keratocyst okc has been a subject of great interest since philipsen introduced the term in 1956. Okc is now referred to by the world health organization who as a keratocystic odontogenic tumour kcot, and who defined it as a benign uni or multicystic, intraosseous tumour of odontogenic origin, with a characteristic lining of parakeratinized stratified squamous epithelium. Child congenital hemidysplasia with ichthyosiform erythroderma and limb defects syndrome is a rare disorder characterized by birth defects of several organ systems, including the skin, viscera, musculoskeletal system, and central nervous system. Odontogenic keratocyst okc is a cyst of tooth origin with an aggressive clinical behavior, including a high recurrence rate. Although there are promising new techniques to treat an odontogenic keratocyst, the most common method of treatment is simply going into the jawbone and removing the odontogenic keratocyst.
A 11yearold female patient reported to the outpatient department of modern dental college and research center, indore, in may 2010, with a complaint of swelling on the right side of the chin that caused considerable asymmetry of the face. Odontogenic keratocyst okc is a developmental cyst that was first described by philipsen 1956. This technique is based on the externalization of the cyst through the creation of a surgical window in the buccal mucosa and in the cystic wall. This technique was used since the complete removal of the cyst posed no risks of complications from a. Keratocystic odontogenic tumors kots are benign lesions occurring in the maxilla or mandible with potential for serious morbidity. Currently, there is no consensus concerning the therapeutic choice for the kcot. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Treatment and cure for odontogenic keratocysts doctor. Odontogenic keratocyst okc is a common developmental odontogenic cyst affecting the maxillofacial region.
The aim of this study was to assess the use of fine needle aspiration cytology fnac in diagnosis of odontogenic keratocyst okc, as well as to describe the cytological and immunohistochemical features. Also known as the keratocystic odontic tumor, it is believed to be stemming from the dental lamina. Surgical treatment of odontogenic keratocyst by enucleation. Nonodontogenic cyst in the oral cavity flashcards quizlet. Conservative treatment protocol of odontogenic keratocyst a preliminary study joms 2006. Clinically, it presents no tendency to relapse due to low local aggressiveness, and is not associated with the nevoid basal cell carcinoma syndrome nbccs 2,4,6. Data sources include ibm watson micromedex updated 10 apr 2020, cerner multum updated 6 apr 2020. In this case, a complete healing of a recurrent okc. The aim of this study was to discuss the aspects regarding the diagnosis, prognosis and treatment of odontogenic keratocyst. It most often affects the posterior mandible and most commonly presents in the third decade of life. Odontogenic keratocyst okc is a cyst that presents local aggression and a high recurrence. Treatment of the odontogenic keratocyst by combined enucleation and. Prevalence, treatment and recurrence of odontogenic.
Surgical treatment of keratocystic odontogenic tumour. Follow these steps to quickly combine and arrange documents. It is now designated by the world health organization as a keratocystic odontogenic tumour kot. Learn how to combine files into a single pdf file using adobe acrobat dc. Reclassification and treatment of odontogenic keratocysts.
The authors hypothesized that keratocystic odontogenic tumors kots would respond to 5fu treatment because of their similarities to bccs in molecular etiopathogenesis. In the whoiarc classification of head and neck pathology, this clinical entity had been known for years as the odontogenic keratocyst. Management of severe odontogenic infections by venezias in types research. The treatment plan consisted of an orthograde retreatment of both premolars. Topical 5fluorouracil is a novel targeted therapy for the. Data sources include ibm watson micromedex updated 10 apr 2020, cerner multum updated 6 apr 2020, wolters kluwer updated.
Conservative management of keratocystic odontogenic tumors. However in 1926 it was first known as a cholesteatoma. Discover everything scribd has to offer, including books and. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Any reversible cause of hair shedding, such as poor diet, iron deficiency, hypothyroidism, or medication use, should be corrected. This technique was used since the complete removal of the cyst posed no risks of complications from a dental andor anatomical point of view. The purpose of this study was to evaluate the different.
1460 624 876 893 1336 1196 1327 818 531 1426 1497 246 457 477 1339 1171 1628 596 667 561 1534 1524 1658 745 220 247 962 409 1431 15 1325 721 377 753 891